Endocrine Abstracts

Anterior pituitary hyperplasia is known to occur with primary hypothyroidism mimicing a pituitary tumour. Massive ovarian enlargement is sometimes associated with juvenile primary hypothyroidism but rarely reported in adults. We report a case of a 23-year-old female who presented with features of a pituitary macroadenoma and bilateral ovarian enlargement which regressed completely with thyroxine therapy.A 23-year-old woman presented with nipple discharge...

Langerhan cell histiocytosis (LCH) is a rare; incidence 1.8/100 000. It affects bone, skin, and pituitary but can involve any organ. Diabetes insipidus (DI) is reported in 15–50% of patients, and anterior pituitary dysfunction in 5–20%. We describe a patient whose diagnosis was delayed because of the challenge in making a tissue diagnosis.A 42-year-old female presented in 2010 with sudden onset deafness and vertigo then 1 year later developed D...